Sample Injectors

 

 


      1. HPLC AutoSamplers                               

 

 

 

 

From built-in sample preparation capabilities to an integrated column oven, Varian HPLC AutoSamplers offer great performance and value.  

High-resolution syringe design for maximum reproducibility
Extensive variety of sample tray and vial types for full flexibility
Cooling and biocompatible options available
Easy-access needle, injector valve, and syringe for quick maintena
   nce

 

 

 


       
Application Type     

 

 

Analytical

Preparative

 Biochromatography

400

410

410

 410

420

 420

 430

 

 430

 

 


       
Easy Operation
          
Varian sample-handling devices have simple, intuitive control interfaces, and can be controlled
          from the module¡¯s keypad or from a Data System, greatly improving ease-of-use and program
          ming capabilities.

        Easy Maintenance
          
Special attention is given to achieving high MTBF (Mean Time Between Failure) and providing
          timely instrument service when needed. Varian HPLC AutoSamplers monitor syringe and inject
          ion valve operation and alert you before injection performance degrades or fails.

         
 

 

 

 

 


    2. 400 AutoSampler                                     

 

 

The 400 is an economical, high-capacity autosampler specifically for automated, routine LC requirements in pharmaceutical, basic chemical, and environmental applications. Like more expensive autosamplers, it boasts a small footprint, high throughput, and rugged design—-all at a surprisingly low price.

 

 

        Performance
       
96-sample capacity makes the 400 very efficient for high throughput, HPLC quality control           procedures.
       
Unique finger valves economize the volume of sample required for precise loop fill injections.
       
A single key stroke makes it easy to start routine automated runs.
       
Automatic calculation of the total and remaining run times improves laboratory efficiency.
       
Four removable racks allow sample preparation while the unit is running.
       
A standard electrically actuated Valco valve with easy access allows quick servicing.
       
Separate wash vials assure minimal carryover for the best results.
       
Optional 5 mL vials allow injection of larger sample volumes.
       
An optional cooling accessory is available for critical temperature sensitive applications.

          


 

 

 

    3. 410 HPLC AutoSampler                               
 

 

 

 

With variable injection volumes and automixing/autodiluting, the ProStar 410 is perfect for laboratories with changing needs. It provides flexible operation without sacrificing reliability or performance.

 

 

 


      
Performance
      
Multiple injection modes offer flexibility, ease of use, and precision. Choose from:
      
Full loop fill — overfills the sample loop for maximum precision.
      
Partial loop fill — allows you to easily program variable injection volumes.
      
Microliter pickup —withdraws the exact amount to be injected without sample loss.
      
Sample trays are available in three configurations: 96 standard 2-mL vials; 84 standard 2-mL
         vials plus three 10-mL vials used for mix solvents; or 24 10-mL vials for large injection volumes.
         These trays can be interchanged in under a minute.
      
Internal standard addition, sample dilution, or derivatization steps are easily programmed to
         reduce sample preparation time and errors associated with manual procedures.

          


 

 

 

    4. 430 AutoSampler                                     
 

 

 

 

The 430 AutoSampler is Varian's most versatile HPLC injection system. Compatible with all types of 96- or 384-well plate formats as well as standard HPLC vials, the 430 is ideal for any of today¡¯s demanding HPLC applications.

 

 

 


     
Performance
     
 Accommodates variable well plate sample trays -- While the 430 handles a wide variety of well
        plates, it also holds conventional 2-ml HPLC vials. With a touch of a button, quickly select from
        96-deep-well plates, standard 96-well plates, 384-well plates, PCR tubes, or 48 standard vials.
     
 Ideal for high throughput LC and LC-MS -- fast cycle times allow analysis of more than 1,500sam
        ples a day.
     
 Metal-free sample path for sensitive samples -- A completely biocompatible PEEK injection valve
        and sample needle are available.
 
     
 For precise sampling, the vial is slightly pressurized by an internal compressor while the syringe
        drive mechanism accurately draws the desired volume into the valve's loop. Without sample loss,
        the microliter pick-up technique positions the sample plug into the center of the loop.

      Precise, reliable injections -- The 430 AutoSampler¡¯s breakthrough loop injection technique with
        Pressure Assisted Sampling (PAS) combines precision with simplicity in a highly reliable design.
        PAS eliminates air bubble problems and sample contamination because it doesn¡¯t use a needle
        port that can easily wear out. The 430 AutoSampler¡¯s high-resolution syringe drive partitions
        syringe movement into 0.004-µl steps and achieves incredible injection precision at 1 µl or less.

     
 Choose from three injection modes -- 1. Full loop injection mode: when there is excess sample,
        the 430 overfills the installed injection loop for the best reproducibility (RSD < 0.3%). 2. Partial         loop-fill injection mode: programmable injections from 1 µ l to 60% of loop volume offer precision
        (RSD < 0.5%) and minimize sample loss. 3. Microliter pickup injection mode: the exact injection         volume is sampled. Then, a wash solvent positions the sample into the loop. There is no sample         loss and reproducibility is better than 1.0% RSD.
 

 

 


          

 

 

 

 



   
5. Injection valve                                                       
 

 

 

 

Switching Valve A
   35MPa(5000psi)±îÁöÀÇ ¾Ð·Â¿¡¼­ À̵¿»óÀÇ flow Áß´Ü ¾øÀÌ(pumpÀÇ
   Á¤Áö ¾øÀÌ) Ä÷³ switchingÀ¸·Î À¯¾Ð°æ·Î¸¦ º¯°æÇÕ´Ï´Ù. ¿¬°á Çü½Ä¿¡
   µû¶ó¼­ ÃÖ´ë 6°³ÀÇ inlet°ú ÇÑ °³ÀÇ outlet switchingÀ¸·Î, ¶Ç´Â ÃÖ´ë 6
   outlet°ú ÇÑ °³ÀÇ inlet switchingÀ¸·Î »ç¿ëµË´Ï´Ù. Ç¥ÁØ accessory·Î´Â
   10-32 thread stainless steel nut¿Í 1/16¡° stainless steel ferruleÀÌ ÀÖ½À
   ´Ï´Ù.

 

 

 

 

 

 

 

Preparative Injection Valve B
   ÀϹÝÀûÀ¸·Î preparative chromatography¿¡¼­ ¸¹Àº ¾çÀÇsample(injection
   loop¸¦ ÀÌ¿ëÇÏ¿© ¹Ð¸®¹ÌÅÍ ±îÁö)À» À̵¿»ó¿¡ ¿¬¼ÓÀûÀ¸·Î ÁÖÀÔÇϴµ¥
   »ç¿ëµË´Ï´Ù. ÃÖ´ë ¾Ð·ÂÀº 35MPa(5000 psi)ÀÔ´Ï´Ù.
   valve B¿¡ ´ëÇÑ injection system°ú sample loop´Â ¿É¼Ç»çÇ×ÀÔ´Ï´Ù.    valve B´Â 3 x 2 switching valve·Îµµ »ç¿ëÀÌ °¡´ÉÇÕ´Ï´Ù.
   Ç¥ÁØ accessory·Î´Â 10-32 thread stainless steel nut¿Í 1/6¡° stainless
   steel ferruleÀÌ ÀÖ½À´Ï´Ù.

 

 

 

 

 

 

 

Analytical Injetion Loop Valve D
   35MPa(5000 psi)±îÁöÀÇ ¾Ð·Â¿¡¼­ HPLC application¿¡ »ç¿ëµË´Ï´Ù.
   loop´Â Hamilton»çÀÇ HPLC¿ë needleÀ̳ª accessory·Î Á¦°øµÈ LUER
   syringe¸¦ ÀÌ¿ëÇÏ¿© ÃæÀüµÇ¾î¾ß ÇÕ´Ï´Ù. injection valve D´Â valve°¡
   INJECT À§Ä¡·Î ¹Ù²î¾úÀ» ¶§ chromatography station°ú ÇÁ·Î±×·¥ÀÌ
   °¡´ÉÇÑ Àåºñ¸¦ µ¿½Ã¿¡ ½ÃÀÛÇÏ´Â ½ºÀ§Ä¡±â´ÉÀ» °¡Áö°í ÀÖ½À´Ï´Ù.
   accessory·Î´Â ¹è¼ö¿ë capillary, 10-32 thread stainless steel nut, 1/16"
   stainless steel ferrule, LUER hub needle, ±×¸®°í connector°¡ ´Þ¸°
   switch ÄÉÀ̺íÀÔ´Ï´Ù. sample loop´Â ¿É¼ÇÇ°¸ñÀÔ´Ï´Ù.  

 

 

 

 

 

 

 

Injection System for Valve B(set)
   ECOM valve B¸¦ Á¶¸³Çϴµ¥ »ç¿ëÇÕ´Ï´Ù. LUER syringe¿ë injection
   systemÀ» Æ÷ÇÔÇÕ´Ï´Ù.

 

 

 

 

 

 

 

 

Stainless Steel Injection Sample Loops 1/16" OD
   analytical injection valve type D¿Í praparative injection valve
   type B¿ëÀ¸·Î Á¦À۵Ǿú½À´Ï´Ù.

 

 

 

 

 

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